GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|
UCEC | cis | rs1577917 | 1 | rs12190604 | chr6:86716215 | SNHG5 | chr6:86386726-86388451:- | -0.45 | -5.47 | 1.81E-7 | Response to antipsychotic treatment |
UCEC | cis | rs1577917 | 1 | rs12192992 | chr6:86609915 | SNHG5 | chr6:86386726-86388451:- | -0.51 | -5.83 | 3.25E-8 | Response to antipsychotic treatment |
UCEC | cis | rs1577917 | 1 | rs12196037 | chr6:86694631 | SNHG5 | chr6:86386726-86388451:- | -0.53 | -5.8 | 3.64E-8 | Response to antipsychotic treatment |
UCEC | cis | rs1577917 | 1 | rs12196411 | chr6:86779762 | SNHG5 | chr6:86386726-86388451:- | -0.52 | -5.73 | 5.22E-8 | Response to antipsychotic treatment |
UCEC | cis | rs9473555 | 1 | rs12196937 | chr6:49382808 | MUT | chr6:49398994-49431031:- | 0.35 | 5.86 | 2.72E-8 | Folate pathway vitamin levels |
UCEC | cis | rs1577917 | 1 | rs12199516 | chr6:86726221 | SNHG5 | chr6:86386726-86388451:- | -0.45 | -5.42 | 2.3E-7 | Response to antipsychotic treatment |
UCEC | cis | rs1577917 | 1 | rs12199784 | chr6:86726808 | SNHG5 | chr6:86386726-86388451:- | -0.47 | -5.84 | 3.13E-8 | Response to antipsychotic treatment |
UCEC | cis | rs1577917 | 1 | rs12200330 | chr6:86656653 | SNHG5 | chr6:86386726-86388451:- | -0.52 | -5.86 | 2.82E-8 | Response to antipsychotic treatment |
UCEC | cis | rs1577917 | 1 | rs12201571 | chr6:86609750 | SNHG5 | chr6:86386726-86388451:- | -0.45 | -5.39 | 2.62E-7 | Response to antipsychotic treatment |
UCEC | cis | rs1577917 | 1 | rs12201735 | chr6:86656939 | SNHG5 | chr6:86386726-86388451:- | -0.43 | -4.96 | 1.83E-6 | Response to antipsychotic treatment |
UCEC | cis | rs1577917 | 1 | rs12201741 | chr6:86602619 | SNHG5 | chr6:86386726-86388451:- | -0.44 | -5.09 | 1.05E-6 | Response to antipsychotic treatment |
UCEC | cis | rs1577917 | 1 | rs12201880 | chr6:86627007 | SNHG5 | chr6:86386726-86388451:- | -0.42 | -4.96 | 1.9E-6 | Response to antipsychotic treatment |
UCEC | cis | rs9473555 | 1 | rs12202075 | chr6:49427655 | MUT | chr6:49398994-49431031:- | 0.35 | 5.81 | 3.59E-8 | Folate pathway vitamin levels |
UCEC | cis | rs1577917 | 1 | rs12203493 | chr6:86758642 | SNHG5 | chr6:86386726-86388451:- | -0.49 | -5.66 | 7.26E-8 | Response to antipsychotic treatment |
UCEC | cis | rs1577917 | 1 | rs12203924 | chr6:86776412 | SNHG5 | chr6:86386726-86388451:- | -0.49 | -5.66 | 7.26E-8 | Response to antipsychotic treatment |